Prevalence of Laboratory Animal Allergy in Laboratory Workers Tae
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IN-DEPTH REVIEW Prevention of laboratory animal allergy
Laboratory animal allergy (LAA) is a common health problem in pharmaceutical research workers. The aetiology of LAA is well established and it is generally accepted that approximately one-third of exposed people may develop symptoms of LAA—see review articles [1,2]. The most common symptoms are rhinitis, conjunctivitis and contact urticaria; ~10% of workers may experience the most serious sympt...
متن کاملMechanism and epidemiology of laboratory animal allergy.
Laboratory animal allergy (LAA) is a form of occupational allergic disease. The development of laboratory animal allergy is due to the presence of IgE antibodies directed against animal proteins. The process of sensitization (development of IgE antibodies) is a complex process which involves interaction of antigen presenting cells and lymphocytes of the Th-2 cell type. These cells generate a ho...
متن کاملAllergy to laboratory animals: an epidemiological study.
A large cross sectional survey was carried out using a self administered questionnaire to examine the prevalence of laboratory animal allergy (LAA) and the factors associated with its development. Out of 5641 workers who were exposed to animals at 137 laboratory animal facilities in Japan, 23.1% had one or more allergic symptoms related to laboratory animals. The commonest symptom as rhinitis. ...
متن کاملA strategy for health surveillance in laboratory animal workers exposed to high molecular weight allergens.
AIMS To develop a health surveillance strategy with the use of diagnostic and prognostic prediction models to detect and predict occupational allergic diseases efficiently. METHODS Data from laboratory animal workers (n = 351) participating in an ongoing cohort study were used to develop diagnostic and prognostic models with logistic regression analyses. A diagnostic model was developed from ...
متن کاملMedical surveillance of allergy in laboratory animal handlers.
Allergic disease is a serious occupational health concern for individuals who have contact with laboratory animals. The principal respiratory symptoms include allergic rhinitis, conjunctivitis, and asthma. Urticaria (" hives") is the most common skin manifestation. The overall prevalence of allergic disease among laboratory animal handlers is about 23%, and respiratory allergy is much more comm...
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تاریخ انتشار 2010